Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract.

Dev Cell · 2020 · PMC7229915 · PMID 32425701

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highly significantno p-value reported

Indeed, in mouse tracheal extracts ( Nemajerova et al., 2016 ) and primary human lung cells ( Martinez-Anton et al., 2013 ), mucociliary differentiation resulted in a highly significant upregulation of ACE2 ( Figures 4 K and 4L).

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