Peripheral Blood Lymphocyte Phenotype Differentiates Secondary Antibody Deficiency in Rheumatic Disease from Primary Antibody Deficiency.

Highly significant were the differences in the proportion of class-switched memory B and CD4 + T follicular T cells, which were matched to abnormally low class-switched memory and abnormally high CD4 + T follicular T cell percentages, suggesting the prominent disease-intrinsic effect on peripheral lymphocyte counts in PID.

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