highly significantp < 0.001
A highly significant and dose-dependent decrease in the percentage of oxidized CoQ10 was observed both at 4 weeks (F = 11.023, p < 0.001) and at 8 weeks (F = 10.087; p < 0.001), although the difference between 4 and 8 weeks was not significant (paired t-test; placebo, p = 0.183; 100 mg/day, p = 0.523; 200 mg/day, p = 0.356).