Novel insights into host-pathogen interactions of large yellow croakers ( <i>Larimichthys crocea</i>) and pathogenic bacterium <i>Pseudomonas plecoglossicida</i> using time-resolved dual RNA-seq of infected spleens.

To remove this, we calculated the P -value of each profile through a specific statistical model, with P <0.001 considered to be an authentic and useful research profile. A total of 50 profiles were aggregated, but only 11 highly significant expression profiles were selected for subsequent analysis ( P <0.001), as shown in Supplementary Figure S1A.

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