The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels.

Biophys J · 2020 · PMC7231921 · PMID 32365329

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an increasing trendno p-value reported

Even if there was a change in conductivity upon 5-s depolarization, the current amplitude displayed an increasing trend in the voltage range between −60 and −20 mV, and only at stronger depolarizations, which in WT channels relieves inactivation, could a small decrease in current be observed.

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