A comparative analysis of unintegrated HIV-1 DNA measurement as a potential biomarker of the cellular reservoir in the blood of patients controlling and non-controlling viral replication.

Indeed, HIV DNA levels expressed as copies/10 4 CD4+ correlated strongly with those expressed as copies/μg of DNA for the 75 patients (r ≥ 0.77, p < 0.0001), and in each subgroup (p ≤ 0.003), with the exception of the Off-ART patients, which, given the small sample size of this group, failed to reach significance (p = 0.15) (Fig. 3 d).

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