Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation.

Compared to NF-co-culture, imCMs co-cultured with AFs exhibited a decreasing trend in action potential duration to 50% repolarization (APD50) and to 90% repolarization (APD90), respectively, while beating frequencies remained similar (Fig. 4g–j ).

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