The cysteine protease ATG4B of Trichinella spiralis promotes larval invasion into the intestine of the host.

The acceleration effect had a dose-dependent relationship with rTsATG4B (r = 0.97, P < 0.01), and the amount of invasion displayed an increasing trend as the rTsATG4B dose increased (F = 52.623, P < 0.01) (Figure 8 B).

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The inhibitory effect of anti-rTsATG4B serum showed a decreasing trend along with an increase in the dilution; thus, invasion also demonstrated a dose-dependent relationship with anti-rTsATG4B serum (r = 0.96, P < 0.01) (Figure 8 D).

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