Optimal Strategies for Mitigating Sudden Cardiac Death Risk in At-risk Patients with Structural Heart Disease.

J Innov Card Rhythm Manag · 2018 · PMC7252838 · PMID 32494485

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

23 The provision of CRT alone was associated with a marginally significant (24%) reduction in all-cause mortality (p = 0.06).

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a trend towards significanceno p-value reported

Prior to this study, no single ICD trial enrolling NICM patients has shown a statistically significant reduction in mortality, although there was a trend towards significance in the DEFINITE and SCD-HEFT trials. 7 , 15 In both studies, the percentages of patients on optimal pharmacological therapies were lower, and no patients received CRT, including those patients with a wide QRS for whom CRT would be indicated.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.