Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations.

PLoS One · 2020 · PMC7259601 · PMID 32469975

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highly significantno p-value reported

SAMP8 mice behaved very poorly: their “total distance travelled” was much reduced compared to the SAMR1 control (a highly significant difference); and they exhibited “passive coping” (i.e. floating) behaviour rather than the normal swimming activity shown by the SAMR1 control strain.

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