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Alterations of functional and structural connectivity in patients with brain metastases.

PLoS One · 2020 · PMC7259727 · PMID 32470024

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an increasing trendno p-value reported
Possibly as a result of improvements in detection and treatment of primary cancers, the incidence of brain metastases has an increasing trend [ 3 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.