borderline significantp =7.41E-08
Although no other SNPs reached genome-wide significance in the conditional analysis, a few borderline significant signals emerged: rs191288953 ( p =7.41E-08; chromosome 7; closest gene SDK1 ) and rs79935880 ( p =7.69E-08; chromosome 10; near MTRNR2L7 ) for C22:0 ceramide levels and rs34432959 ( p =8.68E-08) and rs12963655 ( p =8.00E-08) for C24:0 ceramide levels, both of which are located near SYT4 on chromosome 18.