However, due to the insufficient number of events in the co-high expression group of the combination F2-GOT2-TRPV1 , there was marginally significant difference found in the overall survival rate of HCC patients between the co-high expression group and the co-low expression group of the protein combination F2-GOT2-TRPV1 ( p = 0.051) ( Figure 8B ).
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Big Data-Based Identification of Multi-Gene Prognostic Signatures in Liver Cancer.
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The highly significant results of both the DFS-related single-gene survival analyses for each of these 39 genes and multivariate analysis confirmed that the above 39 genes have a strong association with the DFS of liver cancer, especially the 5-year disease free survival rate of liver cancer.
Three genes ( APOB, PPAT , and TRPV1 ) were associated with both DFS and OS of HCC, suggesting that APOB, PPAT , and TRPV1 may be significant and effective in predicting both the progress and the adverse outcomes of HCC.