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Preclinical safety and efficacy of 24R,25-dihydroxyvitamin D<sub>3</sub> or lactosylceramide treatment to enhance fracture repair.

J Orthop Translat · 2020 · PMC7270532 · PMID 32518749

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an increasing trendno p-value reported
Mineral homeostasis and bone turnover Total ALP showed an increasing trend on Days 18 and 21 postosteotomy for both 24,25(OH) 2 D 3 ( Fig. 1 A) and LacCer ( Fig. 1 E) supplementation, and this increase was statistically significant for the 24,25(OH) 2 D 3 treatment on Day 18 compared to vehicle-treated mice.

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