Meta-analysis of drug efficacy in adult vs pediatric trials of patients with PGTC seizures.

Neurology · 2020 · PMC7274844 · PMID 32238509

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may be significantno p-value reported

It is important to highlight that there may be significant differences in tolerance, side effects, and pharmacokinetics between adults and children treated with antiseizure drugs for PGTCS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.