Protective Efficacy of Inhaled BCG Vaccination Against Ultra-Low Dose Aerosol <i>M. tuberculosis</i> Challenge in Rhesus Macaques.

Pharmaceutics · 2020 · PMC7284565 · PMID 32344890

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

close to significancep = 0.06so close (0.05 < p ≤ 0.1)

tuberculosis -specific CD4 T-cell TNF-α production in vitro [ 33 ], were detected at significantly (or close to significance, p = 0.06 , for IL-5) higher concentrations in aerosol-vaccinated animals two weeks after vaccination. 3.9.

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failed to reach significanceno p-value reported

tuberculosis quantified in extra-thoracic (secondary) sites of infection was significantly reduced by aerosol BCG vaccination relative to unvaccinated animals, whereas the reduction in bacterial load measured in ID BCG-vaccinated animals failed to reach significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.