The carB gene of Escherichia coli , which encodes a subunit of carbamoyl-phosphate synthetase, was proposed to be formed by the duplication of an ancestral gene, since its amino acid sequence shows a highly significant homology between the amino- and carboxyl-terminal halves of the protein [ 10 ].
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The Role of Gene Elongation in the Evolution of Histidine Biosynthetic Genes.
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