Plasma transferrin and hemopexin are associated with altered Aβ uptake and cognitive decline in Alzheimer's disease pathology.

Alzheimers Res Ther · 2020 · PMC7285604 · PMID 32517787

Europe PMC DOI

hedged sentences

0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

failed to reach significancep = 0.081so close (0.05 < p ≤ 0.1)

Higher levels of hemopexin were associated with lower CDR scores that failed to reach significance ( β = − 0.064, p = 0.081; Fig. 1 d).

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an increasing trendno p-value reported

This is supported by our finding of an increasing trend of Hbα associated with increased hippocampal volume in CN individuals (adjusted for conversion status), but the relationship was found to be the converse for Hbβ, suggesting perturbations in heme biology is an early event in AD pathogenesis (Fig. 5 ).

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