Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation.

Environ Health Perspect · 2020 · PMC7289393 · PMID 32525701

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highly significantno p-value reported

These observations are highly significant because recent evidence suggests that cancer may originate from transformation of resident tissue stem cells that self-renew and differentiate into abnormal progeny that continuously seed tumor growth ( Blanpain 2013 ; White and Lowry 2015 ).

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