Psychometric Properties of the Verbal Affective Memory Test-26 and Evaluation of Affective Biases in Major Depressive Disorder.

Patients tended to remember more negative words relative to positive words compared to healthy controls at borderline significance ( p = 0.06), and affective memory biases were negatively associated with depressive symptoms across the two groups at borderline significance ( p = 0.07), however, the effect sizes were small.

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We observed a main overall effect of group on VAMT Bias scores across IMR, STM, and LTM, at a statistical trend level ( p = 0.06), where patients with MDD tended to recall more negative words than positive words compared to healthy controls who recalled more positive words compared to negative words.

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Higher IQ was associated with better recall of all VAMT-26 outcomes (β range: 0.05–0.64, p s ≤ 0.04), except for STM Negative, which was of borderline significance ( p = 0.08).

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In continuation of this, it is also possible that our large sample of patients with MDD and healthy controls has transformed small differences in affective memory bias into borderline significant differences.

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