Gestational Exposure to Sodium Valproate Disrupts Fasciculation of the Mesotelencephalic Dopaminergic Tract, With a Selective Reduction of Dopaminergic Output From the Ventral Tegmental Area.

We observed a marked and highly significant difference in the abundance of TH+ units of MT tract: the value of VPA exposed animals was reduced by 73.3%, i.e., to less than one-third of the value of control animals ( Figure 5 ).

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