Pathway Analysis of Genes Identified through Post-GWAS to Underpin Prostate Cancer Aetiology.

Of those, cancer immune system related programmed cell death protein 1 (PD-1) and its ligand (PD-L1), endosomal/vacuolar and OX40 signalling pathways were among the highly significant pathway enrichments ( Figure 2 A, Table S2 ).

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The adjusted p -value for CTNNB1 revealed a borderline significance threshold (FDR = 0.05) for the upstream regulatory analysis of non-HLA genes ( Table S4 ).

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