IL-12 Signaling Contributes to the Reprogramming of Neonatal CD8⁺ T Cells.

neonatal T cells CD8 + T cells RNA-sequencing IL-12 T cell activation neonatal immunity Institut National de la Santé et de la Recherche Médicale 10.13039/501100001677 Ligue Contre le Cancer 10.13039/501100004099 Agence Nationale de la Recherche 10.13039/501100001665 Next, we analyzed the patterns of gene expression changes after TCR or TCR-IL12 stimulation, considering only highly significant differential genes (adjusted p < 0.05 and log 2 fold change ≥ 2) after TCR or TCR-IL12 stimulation ( Figure 2A ).

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