The rate of mucosal bft positivity in colorectal cancer showed an increasing trend between stage I and stage IV, although this trend was not statistically significant (72.7% and 100%, respectively). 38 In order to eliminate confounding in the microbiome detection resulting from preoperative antibiotics, bft detection was done among patients with different stages of colorectal cancer undergoing mechanical preparations and not oral administration of antibiotics, with similar frequencies to those observed previously. 38 E. coli strain 11G5, a member of the B2 phylogroup, possesses a pks gene island encoding colibactin.
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Clinical Implications of the Associations Between Intestinal Microbiome and Colorectal Cancer Progression.
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