Microneutralization assay titer correlates analysis in two phase 3 trials of the CYD-TDV tetravalent dengue vaccine in Asia and Latin America.

PLoS One · 2020 · PMC7295445 · PMID 32542024

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For DENV-4, cumulative endpoint rates decreased with increasing Month 13 serotype-matched titers in both treatment groups, with low cumulative DENV-4 rates at low titers (Panels G and H of Fig 6 ), and a borderline significant result that the rate was lower in the vaccine group at low titers.

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