Therefore, we hypothesized that miR-181c-5p may play pancreatic-specific functions, and investigating the mechanism of miR-181c-5p in the formation of pancreatic β-like cells and adjusting the differentiation methods are highly significant for the regeneration of functional β cells.
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microRNA-181c-5p promotes the formation of insulin-producing cells from human induced pluripotent stem cells by targeting smad7 and TGIF2.
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