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Factors influencing in-hospital death for pediatric patients with isolated methylmalonic acidemia: a nationwide inpatient database analysis.

Orphanet J Rare Dis · 2020 · PMC7304167 · PMID 32560656

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a decreasing trendno p-value reported
We also found a decreasing trend in in-hospital death among patients over time, which may suggest the effectiveness of the abovementioned guidelines.

also in 47,180 other papers

an increasing trendno p-value reported
We have previously reported an increasing trend in the proportion of admissions for patients diagnosed with MMA from 2013 to 2017 [ 17 ].

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.