However, a decreasing trend in SRD5A2 gene expression was noted (Fig. 1 ).
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Early upregulation of AR and steroidogenesis enzyme expression after 3 months of androgen-deprivation therapy.
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The sentences
In the ADT-PCa group, AR protein expression showed an increasing trend in the ADT ≤12 months subgroup and was significantly elevated in the ADT > 12 months subgroup compared with the PCa group (100%; p < 0.01).