FERM domain-containing protein 6 identifies a subpopulation of varicose nerve fibers in different vertebrate species.

In three independent neuroimaging genetics association studies, a highly significant correlation of the FRMD6 gene to Alzheimer’s disease and mild cognitive impairment was discovered and this correlation was additionally validated by a genome-wide and gene-based association study in a large patient cohort (Hong et al. 2012 ; Shen et al. 2014 ).

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