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Incidence and mortality trend of congenital heart disease at the global, regional, and national level, 1990-2017.

Medicine (Baltimore) · 2020 · PMC7306355 · PMID 32502030

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an increasing trendno p-value reported
Moreover, an increasing trend in CHD mortality was mainly observed in countries with non-advanced economy, such as North Korea and Pakistan.

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a decreasing trendno p-value reported
Regarding CHD subtype, the incidence rate of single ventricle and single ventricle pathway congenital heart anomalies was declined in all 5 SDI regions, and a decreasing trend in severe congenital heart anomalies excluding single ventricle heart defects incidence was found in all SDI regions with the exception of high-middle-SDI region, in which the incidence rate remained stable (AAPC = 0.08, 95%CI: -0.06, 0.22) (Table 2 ).

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