A comparative assessment of clinical parameters, sialic acid, and glycosaminoglycans levels in periodontitis patients with and without dental fluorosis: A clinical and biochemical study.

As the degree of fluorosis increased, periodontitis also increased when gingivitis showed a decreasing trend.[ 14 ] Vandana and Reddy in 2007 reported that as the degree of fluorosis increased, severity of gingivitis reduced and periodontitis increased.[ 15 ] The estimation and comparison of biomarkers like SA and CS were done for the first time in FG and periodontitis patients.

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Similarly, the GCF CS showed highly significant levels in fluorosis periodontitis (48.08 ± 18.13) group than the NFP group (26.95 ± 8.69).

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