Addictovigilance contribution during COVID-19 epidemic and lockdown in France.

There may be an increased risk of opioid overdose arising from i) erratic access to OMT, ii) erratic access to illicit opioid supplies and iii) increased access to takeaway doses of methadone, which would have required the systematic prescription for take-home naloxone supplies [27] : • there was also a growing concern about the risk of overdose with methadone (or of accidental exposure because of lockdown and provision of takeaway methadone at home), as methadone was already the first substance involved in drug abuse-related deaths before the disease outbreak, with an increasing trend in the last years [28] .

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