Apoptotic and anti-proliferative effect of guanosine and guanosine derivatives in HuT-78 T lymphoma cells.

In addition, in later experiments, we also demonstrated that 100 μM of 2′-GMP (potential metabolite of 2′,3′-cGMP) and 3′-GMP (potential metabolite of 2′,3′- and 3′,5′-cGMP) exerted a highly significant apoptotic effect after 72 h of incubation (Fig. 3b ) .

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