Changes in scaffold porosity during bone tissue engineering in perfusion bioreactors considerably affect cellular mechanical stimulation for mineralization.

Bone Rep · 2020 · PMC7315008 · PMID 32613033

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a decreasing trendno p-value reported

However, the surface area fraction of ECM/cell that experienced a WSS of 10–30 mPa (for mineralization) had a decreasing trend ( Fig. 6 ) due to the increasing local WSS at the cell/ECM surface.

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