Integration of Transcriptome, Gross Morphology and Histopathology in the Gill of Sea Farmed Atlantic Salmon (<i>Salmo salar</i>): Lessons From Multi-Site Sampling.

When such analysis was performed on the gene expression profiles indicative of multifactorial gill disease, IPA identified 15 top upstream regulators associated with 101 of the 235 submitted DEGs, all highly significant (overlap P -value < 0.0001) and activated ( z -score > 2) ( Figure 7 and Supplementary Table 9 ).

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