Genome-Wide Identification of a Regulatory Mutation in BMP15 Controlling Prolificacy in Sheep.

The highly significant genetic association with the extreme LS phenotype, the significant effect of the A variant on increasing prolificacy by + 0.2 lamb per lambing in a large set of NV ewes, also found in the BMC genetic background, and the demonstrated action on BMP15 transcriptional activity all support the causality of this mutation named FecX N .

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