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Application of Next-Generation Sequencing to Reveal How Evolutionary Dynamics of Viral Population Shape Dengue Epidemiology.

Front Microbiol · 2020 · PMC7318875 · PMID 32636827

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an increasing trendno p-value reported
In nostructural protein, the study conducted in Cuba also identified an increasing trend of synonymous variant toward the end of the epidemic, particularly among dengue patients with secondary infections ( Rodriguez-Roche et al., 2016 ).

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