Regulatory Role of the Transcription Factor Twist1 in Cancer-Associated Muscle Cachexia.

Front Physiol · 2020 · PMC7324683 · PMID 32655411

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highly significantno p-value reported

Along these lines, both genetic and pharmacological inactivation of Twist1 function was highly significant at protecting against cancer cachexia, which translated into a significant survival benefit in the experimental PDAC animals.

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