Correlation of Clinical Symptoms and Sputum Inflammatory Markers with Air Pollutants in Stable COPD Patients in Beijing Area.

Regarding the hysteresis effect, PM 2.5 showed the strongest correlation with MMP-9 at lag 2 and then showed a decreasing trend;PM 2.5 showed the strongest correlation with IL-8 at lag 2 and then showed a decreasing trend, but there was no significant correlation with CXCL10 or CCL18.PM 10 and NO 2 showed the strongest correlation with MMP-9 and IL-8 at lag 2 and then showed a decreasing trend, but there was no significant correlation with CXCL10 or CCL18.SO 2 showed the strongest correlation with CXCL10 and CCL18 at lag 6 but no significant correlation with MMP-9 or IL-8.CO showed the strongest correlation with MMP-9 and IL-8 at lag 4 but showed no correlation with CXCL10 and CCL18 ( Table 4 and Figure 2 ).

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