Bioenergetic shift and actin cytoskeleton remodelling as acute vascular adaptive mechanisms to angiotensin II in murine retina and ophthalmic artery.

4 b, with an overall trend of decreased activity, as evidenced by the negative z-scores of the four major pathways comprising the oxidative phosphorylation (z-score = -1.134), eukaryotic translation initiation factor (EIF2) signalling (z-score = -1.134), adenosine monophosphate-activated protein kinase (AMPK) signalling (z-score = -1.414) and the sirtuin signalling pathways (z-score = -0.378).

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