Prostate SBRT: Comparison the Efficacy and Toxicity of Two Different Dose Fractionation Schedules.

Of note, there is a statistically significant lower median PSA nadir in the high dose group at 4 years ( p = 0.047), a borderline significant lower nadir in the high dose group at 5 years ( p = 0.073), and a widening of the gap in the percentage of patients achieving ablation PSA results (<0.1 ng/mL) between dose groups at each follow-up interval after 1 year, with ablation PSA results achieved in 62 vs. 44% in the high vs. moderate dose groups by 5 years ( p = 0.11).

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