Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity.

Both the model type and animal had a highly significant effect on the median percent error of the model fit to individual LFP channels, although there is no significant interaction (Model: F (1,144) =25.9, p=1.1×10 −6 ; Animal: F (5,144) =30.2, p=6.3×10 −21 ; Model x Animal: F (5,144) =1.65, p=0.15; two-way ANOVA unequal groups).

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Therefore, it may be significant that local Process S reflects global sleep-wake history more closely than the history of local activity, supporting the idea of a spatial integration of Process S.

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