Comparative analysis of somatic variant calling on matched FF and FFPE WGS samples.

BMC Med Genomics · 2020 · PMC7336445 · PMID 32631411

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highly significantno p-value reported

Subsequently, many of the highly significant calls belong to the major subpopulation at a VAF of 0.25 in the FF and 0.15 in the FFPE sample; such that the analysis of the significance levels and the clonal subpopulations points at the existence of a highly confident subset of variants, present in both the FF and the FFPE samples.

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