Barely Significant
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Influences of preoperative metformin on immunological factors in early breast cancer.

Cancer Chemother Pharmacol · 2020 · PMC7338817 · PMID 32533334

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an increasing trendno p-value reported
We did not identify a statistically significant increase in TILs, CD4 + or CD8 + lymphocytes with preoperative metformin, but an increasing trend was noted.

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