a trend towards significancep = 0.059
In summary, revised Figure 1 now demonstrates (A) statistically significant effect of probiotic treatment on the distance moved in the light zone when mice of both sexes are considered in the analyses, (B) statistically significant effect of probiotic treatment on the distance moved in the light zone in female mice, which appear to drive the overall effect, and (C) a trend towards significance for the time spent in the light zone when both sexes are considered (p = 0.059), with probiotic-treated animals spending 10% more time in the light zone.