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Hepatitis B Seroprevalence in the Pediatric and Adolescent Population of Florence (Italy): An Update 27 Years after the Implementation of Universal Vaccination.

Vaccines (Basel) · 2020 · PMC7348992 · PMID 32235670

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a decreasing trendno p-value reported
In the last three decades, the Italian epidemiological landscape regarding hepatitis B has changed profoundly, with a decreasing trend of incidence and prevalence of the hepatitis B infection.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.