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Safety Surveillance of Pneumococcal Vaccine Using Three Algorithms: Disproportionality Methods, Empirical Bayes Geometric Mean, and Tree-Based Scan Statistic.

Vaccines (Basel) · 2020 · PMC7349998 · PMID 32456068

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an increasing trendno p-value reported
According to a previous study on the impact of the publicly funded PCV immunization program on the number of hospitalized cases of orbital cellulitis, a bacterial infection of the post-septal tissues of the eye, there was an increasing trend from 0.39 cases to 0.90 cases per 1000 admissions before and after introduction of the immunization program, respectively [ 40 ].

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