Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.

J Diabetes Res · 2020 · PMC7352126 · PMID 32685554

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marginal significanceno p-value reported

Among South Africa-Mixed Ancestry, TCF7L2-rs7903146 showed marginal significance whereas TCF7L2-rs12255372 was not significantly associated with T2DM [ 56 ]. 3.6.

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near significanceno p-value reported

Of the three polymorphisms in the FTO gene reported in two studies in two black South African mixed ancestry population, only rs9941349 (OR = 1.43 (1.00-2.04), p = 0.052) was near significance, associated with T2DM after adjustment for cofounders [ 56 ].

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