Because this difference is highly significant, it is possible that downregulation of NRBP2 may reflect an immature, progenitor-like state of MB cells, and that loss, or reduction, of NRBP2 expression during tumor formation relates to an undifferentiated state by which MB aggressiveness increases.
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Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression.
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