Vascular Decoupling in Septic Shock: The Combined Role of Autonomic Nervous System, Arterial Stiffness, and Peripheral Vascular Tone.

After full resuscitation with fluids and vasopressors (T4), the hypoperfusion and hypovolemic condition was restored as MAP increased to >60 mmHg, SV returned to values similar to baseline, SvO 2 increased becoming higher than baseline values, and all the main hemodynamic indices, e.g., CO, SAP, DAP, showed a positive trend, i.e., the differences between the values at T4 and T2 were positive ( Table 1 ).

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On the opposite, an increasing trend was observed for the FF gain, or runoff effect, which was higher compared to baseline both in shock and after resuscitation.

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